KEGG   Homo sapiens (human): 8317
Entry
8317              CDS       T01001                                 
Symbol
CDC7, CDC7L1, HsCDC7, Hsk1, huCDC7
Name
(RefSeq) cell division cycle 7
  KO
K02214  cell division control protein 7 [EC:2.7.11.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04110  Cell cycle
Network
nt06509  DNA replication
  Element
N01468  DNA replication licensing
Drug target
Simurosertib: D12176
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    8317 (CDC7)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    8317 (CDC7)
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:hsa03032]
    8317 (CDC7)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     8317 (CDC7)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: Other
  CDC7 family
   8317 (CDC7)
DNA replication proteins [BR:hsa03032]
 Eukaryotic type
  DNA Replication Initiation Factors
   DDK (Dbf-4 dependent kinase)
    8317 (CDC7)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr APH ABC1
Other DBs
NCBI-GeneID: 8317
NCBI-ProteinID: NP_001127891
OMIM: 603311
HGNC: 1745
Ensembl: ENSG00000097046
UniProt: O00311 A0A384MTU6
Structure
Position
1:91500851..91525764
AA seq 574 aa
MEASLGIQMDEPMAFSPQRDRFQAEGSLKKNEQNFKLAGVKKDIEKLYEAVPQLSNVFKI
EDKIGEGTFSSVYLATAQLQVGPEEKIALKHLIPTSHPIRIAAELQCLTVAGGQDNVMGV
KYCFRKNDHVVIAMPYLEHESFLDILNSLSFQEVREYMLNLFKALKRIHQFGIVHRDVKP
SNFLYNRRLKKYALVDFGLAQGTHDTKIELLKFVQSEAQQERCSQNKSHIITGNKIPLSG
PVPKELDQQSTTKASVKRPYTNAQIQIKQGKDGKEGSVGLSVQRSVFGERNFNIHSSISH
ESPAVKLMKQSKTVDVLSRKLATKKKAISTKVMNSAVMRKTASSCPASLTCDCYATDKVC
SICLSRRQQVAPRAGTPGFRAPEVLTKCPNQTTAIDMWSAGVIFLSLLSGRYPFYKASDD
LTALAQIMTIRGSRETIQAAKTFGKSILCSKEVPAQDLRKLCERLRGMDSSTPKLTSDIQ
GHASHQPAISEKTDHKASCLVQTPPGQYSGNSFKKGDSNSCEHCFDEYNTNLEGWNEVPD
EAYDLLDKLLDLNPASRITAEEALLHPFFKDMSL
NT seq 1725 nt   +upstreamnt  +downstreamnt
atggaggcgtctttggggattcagatggatgagccaatggctttttctccccagcgtgac
cggtttcaggctgaaggctctttaaaaaaaaacgagcagaattttaaacttgcaggtgtt
aaaaaagatattgagaagctttatgaagctgtaccacagcttagtaatgtgtttaagatt
gaggacaaaattggagaaggcactttcagctctgtttatttggccacagcacagttacaa
gtaggacctgaagagaaaattgctctaaaacacttgattccaacaagtcatcctataaga
attgcagctgaacttcagtgcctaacagtggctggggggcaagataatgtcatgggagtt
aaatactgctttaggaagaatgatcatgtagttattgctatgccatatctggagcatgag
tcgtttttggacattctgaattctctttcctttcaagaagtacgggaatatatgcttaat
ctgttcaaagctttgaaacgcattcatcagtttggtattgttcaccgtgatgttaagccc
agcaattttttatataataggcgcctgaaaaagtatgccttggtagactttggtttggcc
caaggaacccatgatacgaaaatagagcttcttaaatttgtccagtctgaagctcagcag
gaaaggtgttcacaaaacaaatcccacataatcacaggaaacaagattccactgagtggc
ccagtacctaaggagctggatcagcagtccaccacaaaagcttctgttaaaagaccctac
acaaatgcacaaattcagattaaacaaggaaaagacggaaaggagggatctgtaggcctt
tctgtccagcgctctgtttttggagaaagaaatttcaatatacacagctccatttcacat
gagagccctgcagtgaaactcatgaagcagtcaaagactgtggatgtactgtctagaaag
ttagcaacaaaaaagaaggctatttctacaaaagttatgaatagtgctgtgatgaggaaa
actgccagttcttgcccagctagcctgacctgtgactgctatgcaacagataaagtttgt
agtatttgcctttcaaggcgtcagcaggttgcccctagggcaggtacaccaggattcaga
gcaccagaggtcttgacaaagtgccccaatcaaactacagcaattgacatgtggtctgca
ggtgtcatatttctttctttgcttagtggacgatatccattttataaagcaagtgatgat
ttaactgctttggcccaaattatgacaattaggggatccagagaaactatccaagctgct
aaaacttttgggaaatcaatattatgtagcaaagaagttccagcacaagacttgagaaaa
ctctgtgagagactcaggggtatggattctagcactcccaagttaacaagtgatatacaa
gggcatgcttctcatcaaccagctatttcagagaagactgaccataaagcttcttgcctc
gttcaaacacctccaggacaatactcagggaattcatttaaaaagggggatagtaatagc
tgtgagcattgttttgatgagtataataccaatttagaaggctggaatgaggtacctgat
gaagcttatgacctgcttgataaacttctagatctaaatccagcttcaagaataacagca
gaagaagctttgttgcatccattttttaaagatatgagcttgtga

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (1)   
   KEGG PATHWAY (1)   
Network (2)   
   KEGG NETWORK (2)   
Disease (1)   
   OMIM (1)   
Drug (1)   
   KEGG DRUG (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (17)   
   KEGG ORTHOLOGY (1)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (5)   
   OC (1)   
Protein sequence (34)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (31)   
DNA sequence (61)   
   RefSeq(nuc) (31)   
   GenBank (15)   
   EMBL (15)   
3D Structure (9)   
   PDB (9)   
Protein domain (4)   
   Pfam (4)   
All databases (136)   

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